Nicholas Boddicker

3 weeks ago | nature.com | Nicholas Boddicker |Thomas M Habermann |Andrew Feldman |Rebecca King |Stephen Ansell |Angela Dispenzieri | +9 more

AbstractWe investigated the prevalence of rare inherited pathogenic variants (PV) in 19 cancer predisposition genes regularly included on multi-gene panel testing based on NCCN guidelines and their association with the risk of lymphoid malignancies (LM) overall and by common lymphoma subtypes and multiple myeloma. The study population included newly diagnosed LM cases (N = 6990) and unrelated controls (N = 42,632), excluding individuals with a history of hematologic malignancy.