Nicholas Fischer

Aug 26, 2024 | nature.com | Ping Luo |Nicholas Fischer |Vallijah Subasri |Adam Shlien |Raymond Kim |David Malkin | +2 more

AbstractGermline pathogenic TP53 variants predispose individuals to a high lifetime risk of developing multiple cancers and are the hallmark feature of Li-Fraumeni syndrome (LFS). Our group has previously shown that LFS patients harbor shorter plasma cell-free DNA fragmentation; independent of cancer status.

Dec 21, 2023 | roanoke.com | Nicholas Fischer

Both high school students who died on Nov. 7 in Blacksburg were victims. Both families are grieving. Both deaths have left some with survivor guilt. Both deaths leave us with many questions and concerns. Key among them is: do we have the services and resources available to respond to the signs that violence like this might happen?

Sep 6, 2023 | mondaq.com | Nicholas Fischer

The new framework was first floated back in January 2023, as a way for the MHRA to streamline the authorisation process by taking advantage of assessments already conducted by "trusted" regulators in other jurisdictions. In May 2023 the MHRA announced the new international partners as Australia, Canada, Japan, Switzerland, Singapore, the US and the EU - building on existing collaborations through programmes such as Project Orbis (something we also predicted earlier in the year).