Nnenna G. Agim

Jul 9, 2024 | onlinelibrary.wiley.com | Ariel Brown |Andrew Park |Nnenna G. Agim |Katherine Gordon

1 INTRODUCTION Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), blistering skin and mucosal eruptions, remain ill-defined in pediatric patients.1 Though guidelines exist, much data are still needed to optimize patient care.2 Emerging new classification for SJS/TEN caused by drugs simplifies clinical diagnostic criteria into a single diagnosis, “drug-induced epidermal necrolysis” (DEN).3 In this report, when SJS/TEN are grouped, the terminology DEN will be used.

Feb 9, 2024 | sciencedirect.com | Nnenna G. Agim |Candrice Heath

Human skin occurs in a kaleidoscope of colors, with different shades evolving as adaptations to varying solar radiation—including UV light —in different geographic locations.1,2 Melanin pigments are protective against the deleterious effects of UV radiation, and melanin content correlates with the prevention of UV-associated DNA damage.2 Skin color can be defined as visible pigmentation associated with the absorption and scattering of light from the epidermis, dermis, and underlying...