Nuno Borges

1 month ago | nature.com | Yaqi Liu |Chelsea Brown |Nuno Borges |Satchal Erramilli |Brian Kloss |Todd L. Lowary | +6 more

AbstractTuberculosis (TB), a leading cause of death among infectious diseases globally, is caused by Mycobacterium tuberculosis (Mtb). The pathogenicity of Mtb is largely attributed to its complex cell envelope, which includes a class of glycolipids called phosphatidyl-myo-inositol mannosides (PIMs). These glycolipids maintain the integrity of the cell envelope, regulate permeability, and mediate host-pathogen interactions.