Nuria Ferrandiz

May 31, 2024 | biorxiv.org | Laura E. Downie |Nuria Ferrandiz |Megan Jones |Stephen J. Royle

AbstractMembrane contact sites (MCSs) are areas of close proximity between organelles that allow the exchange of material, among other roles. The endoplasmic reticulum (ER) has MCSs with a variety of organelles in the cell. MCSs are dynamic, responding to changes in cell state, and are therefore best visualized through inducible labeling methods. However, existing methods typically distort ER-MCSs, by expanding contacts or creating artificial ones.