Ofir Frenkel

Nov 21, 2023 | onlinelibrary.wiley.com | Robert F. Kushner |Anders Fink-Jensen |Ofir Frenkel

What is already known? There is a strong bidirectional link between obesity and depression. Several antidepressants have been shown to induce weight gain, thus increasing the risk of obesity. People with depressive episodes are often excluded from weight loss trials. Participants with major depressive disorder or other severe psychiatric disorders, such as schizophrenia or bipolar disorder, were excluded from the STEP program.