Olena Iakunchykova

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Articles

Genetic evidence for causal effects of immune dysfunction in psychiatric disorders: where are we? - Translational Psychiatry

Jan 25, 2024 | nature.com | Olena Iakunchykova |Yunpeng Wang

AbstractThe question of whether immune dysfunction contributes to risk of psychiatric disorders has long been a subject of interest. To assert this hypothesis a plethora of correlative evidence has been accumulated from the past decades; however, a variety of technical and practical obstacles impeded on a cause-effect interpretation of these data.
Circulating S100B levels at birth and risk of six major neuropsychiatric or neurological disorders: a two-sample Mendelian Randomization Study - Translational Psychiatry

May 24, 2023 | nature.com | Ron Nudel |Olena Iakunchykova |Anders M. Fjell |Kristine B. Walhovd |Thomas Werge |Michael E. Benros

AbstractCirculating levels of the astrocytic marker S100B have been associated with risk of neuropsychiatric or neurological disorders. However, reported effects have been inconsistent, and no causal relations have yet been established.

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