Omar F Cruz-Correa

Dec 1, 2024 | jrheum.org | Rachel Offenheim |Omar F Cruz-Correa |Darshini Ganatra |Dafna D Gladman

Key Indexing Terms: biologics biomarkers psoriasis psoriatic arthritis Psoriasis is an inflammatory skin disease mediated by activation of T lymphocyte and innate immune cells leading to keratinocyte hyperproliferation.1,2 Activated T cells produce tumor necrosis factor-α (TNF-α) and interleukins (IL; IL-23, IL-12, and IL-6).2 Subsequently, keratinocytes cause more inflammation through the release of cytokines and chemokines including chemokine ligand 20 (CCL20), C-X-C motif chemokine ligand...

Sep 24, 2024 | jrheum.org | Rachel Offenheim |Omar F Cruz-Correa |Darshini Ganatra |Dafna D Gladman

Candidate Biomarkers for Response to Treatment in Psoriatic Disease Rachel Offenheim, Omar F. Cruz-Correa, Darshini Ganatra, Dafna D. Gladman The Journal of Rheumatology Sep 2024, jrheum.2024-0396; DOI: 10.3899/jrheum.2024-0396

Aug 24, 2024 | jrheum.org | Omar F Cruz-Correa |Dafna D Gladman |Rachel Offenheim |Darshini Ganatra

Candidate Biomarkers For Response To Treatment In Psoriatic Disease Rachel Offenheim, Omar F. Cruz-Correa, Darshini Ganatra, Dafna D. Gladman The Journal of Rheumatology Sep 2024, jrheum.2024-0396; DOI: 10.3899/jrheum.2024-0396

Jul 19, 2023 | onlinelibrary.wiley.com | Omar F Cruz-Correa |Remy A Pollock |Rohan Machhar |Dafna D Gladman

Full Length This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1002/art.42654.

Jul 18, 2023 | pericles.pericles-prod.literatumonline.com | Remy A Pollock |Dafna D Gladman |Omar F Cruz-Correa |Rohan Machhar

Abstract Objective Psoriatic arthritis (PsA) is an immune-mediated inflammatory arthritis, associated with psoriasis, that significantly increases morbidity and mortality risk. We currently lack the means of predicting which psoriasis patients will develop PsA, and a large number of patients remain undiagnosed. Regulation of gene expression through DNA methylation can potentially trigger and maintain PsA pathophysiological processes.