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Nov 1, 2024 | 
jitc.bmj.com | JAMES GULLEY |Ryan Sullivan |Claire F. Friedman |P Sonpavde
AbstractBackground Invikafusp alfa, a dual T cell agonist, promotes the selective activation and expansion of Vβ6/Vβ10 TCR-expressing CD8+ and CD4+ effector memory T cells, which in nonclinical studies promote potent anti-tumor activity in anti-PD(L)1-resistant solid tumors.1 2Methods START001 is a first-in-human, multicenter Phase 1/2 study evaluating invikafusp as monotherapy in patients with anti-PD(L)1-resistant, antigen-rich solid tumors (TMB-H, MSI-H/dMMR, or virally associated).
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Oct 30, 2023 | 
opmed.doximity.com | Margaret Nichols |Lisa Carey |P Sonpavde
My hand is outstretched. The room is quiet, but with that underlying hum of concentrated activity that occurs when multiple people are intensely and efficiently completing the many tasks necessary for the patient to have a successful outcome. The pace is quick but confident. Without a word, I feel the necessary instrument placed in my hand. My attention to the procedure, removing the thick layer of clotted blood from the surface of the patient’s brain, never varies.
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Oct 30, 2023 | 
opmed.doximity.com | Mohammad Ali Al-Haddad |Sarah Stainko FNP-C |Lisa Carey |P Sonpavde
Physician Mentorship Is Key To Growing an Engaged Advanced Practice Provider WorkforceThe American College of Gastroenterology's annual scientific meeting held each year is a time to be involved, engaged, and present in gastroenterology.
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Oct 30, 2023 | 
opmed.doximity.com | Alexander Yang |Rohit Loomba |Lisa Carey |P Sonpavde
As the autumn foliage gives way to winter snow, The Liver Meeting is upon us once again! This year we are back in the historic Back Bay of Boston ay Hynes Convention Center to meet our friends and colleagues around the world. UCSD is proud and excited to share our research endeavors with researchers and clinicians to help improve care across the globe.
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Oct 30, 2023 | 
opmed.doximity.com | P Sonpavde |Lisa Carey
The ESMO annual conference in 2023 brought the most remarkable advances in the first-line therapy of metastatic urothelial carcinoma (mUC) since the establishment of platinum-based chemotherapy approximately 3 decades ago. The backdrop is that first-line therapy of mUC recently evolved based on the JAVELIN-Bladder-100 Phase III trial to the administration of switch maintenance avelumab (PD-L1 inhibitor) following stable or responding disease with 4-6 cycles of platinum-based chemotherapy.
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Oct 30, 2023 | 
opmed.doximity.com | Lisa Carey |P Sonpavde
ESMO 2023 was its usual chaotic wonderful self, with tens of thousands of attendees and great clinically relevant scientific presentations. The increasing importance of immune checkpoint blockade in breast cancer was highlighted by several presentations.
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Jun 12, 2023 | 
opmed.doximity.com | P Sonpavde |Richard Goldberg |Lisa Carey |Danielle Pigneri
Op-Med is a collection of original articles contributed by Doximity members. Presentations at the ASCO annual conference in 2023 consolidated the recent advances in the therapy and understanding of major GU cancers.
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Jun 12, 2023 | 
opmed.doximity.com | Lisa Carey |P Sonpavde |Danielle Pigneri
Op-Med is a collection of original articles contributed by Doximity members. The treatment landscape for endocrine therapy (ET) in hormone receptor-positive (HR+) and HER2-negative (HER2-) breast cancer has been remarkably changed over the past 10 years. In addition to the development of increasingly effective ET drugs, we have the benefit of a portfolio of “helper” drugs that augment effectiveness of ET in both the metastatic and nonmetastatic settings, particularly the CDK4/6 inhibitors.
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Mar 2, 2023 | 
opmed.doximity.com | Lloyd D Holm |Caitlin Cain |Olapeju M. Simoyan |P Sonpavde
Op-Med is a collection of original articles contributed by Doximity members. Effective teachers have always been a source of inspiration, and early in my academic and medical odyssey, I made a conscious effort to emulate them. Becoming an effective teacher goes beyond individual mannerisms, techniques, or props. It goes to the essence of what effective teaching really is.
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Mar 2, 2023 | 
opmed.doximity.com | Caitlin Cain |Olapeju M. Simoyan |P Sonpavde |Julie Gralow
Op-Med is a collection of original articles contributed by Doximity members. When I moved to New York to start surgical residency — now over a year ago — I went to see an Alice Neel exhibit at the Metropolitan Museum of Art. Alice Neel is a 20th century American portrait artist, known to the art world as a militant feminist for her depiction of women's nudes through a woman's gaze, but she also brilliantly depicted Americans from all walks of life, one being sickness.
