Pablo Ballester

May 21, 2024 | pubs.rsc.org | Pablo Ballester |Esteban J. Valencia

Conformational preorganization of a water-soluble tetra-carboxylate aryl-extended calix[4]pyrrole enhances its binding towards methyl-alkylammonium cations The binding of pyridine-N-oxide in the large polar aromatic cavity of a water soluble tetra-α aryl-extended calix[4]pyrrole (C[4]P) results in the quantitative self-assembly of a supramolecular receptor featuring the pyrrole rings preorganized in cone conformation and displaying improved binding properties (log K = 3 - 4) towards a series...