Paloma Moraga

2 months ago | biorxiv.org | Eduardo A. Sagredo |Alejandro Blanco |Paloma Moraga |Victor Karlstrom

AbstractAdenosine-to-inosine (A-to-I) RNA editing and alternative splicing occur co-transcriptionally and can regulate and influence each other. The RNA editing enzymes ADAR1 and ADAR2 catalyze A-to-I RNA editing, where it has been shown that expression changes in both RNA editing enzymes exert alternative splicing. ADAR1 manipulation has a significant impact on alternative splicing.