Paola Cornejo-Páramo

Jan 14, 2024 | biorxiv.org | Paola Cornejo-Páramo |Veronika Petrova |Xuan Zhang |Robert Young

AbstractEnhancers are fast-evolving genomic sequences that control spatiotemporal gene expression patterns. By examining enhancer turnover across mammalian species and in multiple tissue types, we uncovered a relationship between the emergence of novel enhancers and genome organization as a function of germline DNA replication time.