Patrick Hyden

Sep 25, 2023 | biorxiv.org | Veronika Young |Bushra Saeed Dohai |Benjamin Weller |Patrick Hyden

AbstractThe molecular mechanisms by which the gut microbiome influences human health remain largely unknown. Pseudomonadota is the third most abundant phylum in normal gut microbiomes. Several pathogens in this phylum can inject so-called virulence effector proteins into host cells. We report the identification of intact type 3 secretion systems (T3SS) in 5 - 20% of commensal Pseudomonadota in normal human gut microbiomes.