Paul Richardson

6 days ago | tandfonline.com | Sagar Lonial |Meletios A. Dimopoulos |Jesus G Berdeja |Paul Richardson

ABSTRACTMultiple myeloma (MM) is a plasma cell neoplasm that stems from the malignant transformation of clonal plasma cells. It is characterized by multiple periods of remission and relapse requiring multiple lines of therapy, with response to treatment and survival decreasing with each successive relapse. To achieve deep and durable responses in relapsed/refractory MM (RRMM), novel treatments are required.

Apr 21, 2024 | nature.com | Natalie S. Callander |Jonathan Kaufman |Jacob P. Laubach |Timothy Schmidt |Brandi N. Reeves |Binod Dhakal | +8 more

AbstractIn the MASTER study (NCT03224507), daratumumab+carfilzomib/lenalidomide/dexamethasone (D-KRd) demonstrated promising efficacy in transplant-eligible newly diagnosed multiple myeloma (NDMM). In GRIFFIN (NCT02874742), daratumumab+lenalidomide/bortezomib/dexamethasone (D-RVd) improved outcomes for transplant-eligible NDMM. Here, we present a post hoc analysis of patients with high-risk cytogenetic abnormalities (HRCAs; del[17p], t[4;14], t[14;16], t[14;20], or gain/amp[1q21]).

Apr 9, 2024 | mdpi.com | Paul Richardson |P. G

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Sep 18, 2023 | bloomberglinea.com | Paul Richardson

ÚltimascotizacionesBloomberg — El gobierno de la República del Congo negó especulaciones en redes sociales de que había tenido lugar un golpe de Estado en el país. “Informaciones fantasiosas sugieren que puede haber graves acontecimientos en curso en Brazzaville”, dijo el portavoz del gobierno Thierry Moungalla en un comunicado publicado en Twitter, refiriéndose a la capital congoleña. “El gobierno desmiente esta noticia falsa”.