Peihan Wang

Jul 15, 2024 | biorxiv.org | Xia Yu |Jie Wang |Peihan Wang |Xiaoqiang Liu

AbstractGranulomas (defining tuberculosis histopathological feature) are central to the host's defense against Mycobacterium tuberculosis, critically influencing patient outcomes. However, knowledge of human granulomas' structure and function are incomplete. This study employs single-cell and spatial transcriptomics to dissect human granuloma's cellular composition, structure, communication and function from 19 pulmonary, lymphatic and skeletal samples.

Jun 19, 2024 | onlinelibrary.wiley.com | Peihan Wang |Wu Chen |Bojun Li |Songyuan Yang

1 INTRODUCTION Renal fibrosis is frequently outcome of chronic kidney disease (CKD) arising from several causes and is characterized by a sequence of pathological alterations, including the infiltration of inflammatory cells, proliferation of fibroblasts, and deposition of extracellular matrix.1 It has been reported that more than half of the adults over 70 years of age are affected by renal fibrosis.2 Sepsis, renal ischaemia–reperfusion, ureteral obstruction, and drug-induced acute kidney...

Mar 11, 2024 | onlinelibrary.wiley.com | Peihan Wang |Jinzhuo Ning |Wu Chen |Fan Zou

1 INTRODUCTION Cytoplasmic dynein-1 (dynein) is involved in a diverse array of functions, such as intracellular transportation of cargo, construction of the spindle apparatus and modulation of several physiological and pathological processes.

Jul 17, 2023 | iubmb.onlinelibrary.wiley.com | Peihan Wang |Wu Chen |Sheng Zhao |Fan Cheng

DATA AVAILABILITY STATEMENT Data available on request from the authors. The data that support the findings of this study are available from the corresponding author upon reasonable request.