Pengyu Zong

May 13, 2024 | biorxiv.org | Emily Meredith |Fraser McGurk |Pengyu Zong |Brian Aguilera

AbstractTransmembrane CD13 assembles protein complexes at the plasma membrane to enable diverse cellular processes such as cell-cell adhesion, focal adhesion turnover, endocytosis and recycling of cell surface proteins. In this study, we demonstrate a novel CD13-dependent assembly platform that regulates phosphoinositide (PI) signal transduction during the formation of Tunneling Nanotubes (TNTs).