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Feb 15, 2025 | 00138-7/fulltext&sz=64)
jcvaonline.com | Sean Hickey |Perioperative Medicine |Christopher Ortiz |Phoebe Black
Key Words extracorporeal membrane oxygenation ECMO extracorporeal cardiopulmonary resuscitation ECPR cardiac arrest emergency medicine critical care resuscitation intensive care shock DESPITE DECADES OF RESEARCH and advances in resuscitation care, out-of-hospital cardiac arrest (OHCA) continues to result in high rates of poor outcomes, including death or devastating neurologic injury.1 Refractory cardiac arrest (sustained or repeated cardiac arrest during advanced cardiac life support [ACLS])...
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Jan 10, 2025 | 
jmedicalcasereports.biomedcentral.com | Perioperative Medicine |Sahlgrenska Academy
A 7-year-old girl of Kurdish ethnicity, with no previous family history of genetic disorders, was diagnosed with HSAN IV CIPA at the age of 5 years. The diagnosis was originally suspected as the child did not notice multiple minor injuries. She was born and raised in Sweden within a well-functioning family, developed intellectually normally until the age of 6 years, and investigation revealed no other medical or dental history related to any other illness.
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Nov 28, 2024 | 
respiratory-research.biomedcentral.com | Mohammad Reza |Perioperative Medicine
The small intestine and lungs of C57Bl6 wildtype mice fed a chow and 15-HETE diet were dissected, and RNA was extracted using mirVana for the intestine and Trizol, followed by a cleanup using RNeasy MinElute Cleanup Kit (Qiagen) according to manufacturer’s instructions, for the lungs. We performed RNA-sequencing on Illumina HiSeq3000 for a single-end 1 × 50 run. The reads were mapped and quantified by STAR 2.7.9a [21] using the mouse genome GRCm39.
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Nov 27, 2024 | 
link.springer.com | Perioperative Medicine |Thomas Jefferson
AbstractScopolamine is a widely used antiemetic in anesthetic practice, particularly for postoperative and post-discharge nausea and vomiting. Despite its frequent usage and recognized efficacy, concerns have emerged regarding the potential for increased side effects, particularly in elderly patients. Further research is needed to assess safety and determine age thresholds for adverse events.
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Nov 25, 2024 | 
systematicreviewsjournal.biomedcentral.com | Virginia Commonwealth |Perioperative Medicine
A mixed studies approach, which appeals to a concomitant examination of qualitative, quantitative, and mixed-methods primary studies, will address the broad purpose of the scope, understanding, and verification of knowledge grounded on all types of empirical research.
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Nov 5, 2024 | 
academic.oup.com | Perioperative Medicine
Mechanosensitive ion channels play a key role in heart development, physiology, and disease. However, little is known about the molecular mechanisms of the mechanosensitive nonselective cationic channel Piezo family in cardiac fibrosis. Mice were treated with ISO/Ang-II/TAC to induce cardiac fibrosis. AAV9 carrying POSTN promoter-driven small hairpin RNA targeting YTHDF1, and Piezo2 were administered to ISO mice to investigate their roles in cardiac fibrosis.
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Oct 23, 2024 | 
systematicreviewsjournal.biomedcentral.com | Perioperative Medicine
MethodsPOCUS in obstetric anesthesiology and critical care is an emerging concept encompassing numerous applications. The literature is expected to be heterogeneous in focus and methodology. Therefore, following the indications and methodological considerations described initially by Arksey and O’Malley, and later Levac, a scoping review methodology is appropriate to map and broadly summarize the literature to date [8, 9].
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Oct 23, 2024 | 
academic.oup.com | Perioperative Medicine
Gabapentin and pregabalin are inhibitory ligands of both α2δ-1 and α2δ-2 proteins (also known as subunits of voltage-activated Ca2+ channels) and are commonly prescribed for the treatment of neuropathic pain and epilepsy. However, these drugs can cause gait disorders and ataxia through unknown mechanisms. α2δ-2 and GluK1, a glutamate-gated kainate receptor subtype, are coexpressed in cerebellar Purkinje cells.
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Oct 20, 2024 | 
bmcnephrol.biomedcentral.com | de la Cruz |Perioperative Medicine
The Institutional Animal Care and Use Committee of the University of Tennessee Health Science Center (UTHSC) approved the study protocol. Mice (C57BL/6J, 8–10 weeks old, Jackson Laboratory, Bar Harbor, ME, USA) were used for the experiments. The mice were housed in UTHSC animal facilities, which provided ad libitum access to food and water. This study was carried out according to the National Institute of Health guidelines for the Care and Use of Laboratory Animals and the ARRIVE guidelines.
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Oct 8, 2024 | 00309-3/fulltext?rss=yes&sz=64)
jclinepi.com | Perioperative Medicine
1Department of Surgery, Division of General Surgery, University of Toronto, Toronto, ON, Canada 2Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada 3Division of Biostatistics, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada 4Department of Medicine, University of Toronto, Toronto, ON, Canada 5Department of Medicine, University Health Network, Toronto, ON, Canada 6Institute for Work & Health, Toronto, ON, Canada...
