Peter Winskill

Oct 16, 2024 | nature.com | Penelope A. Hancock |Adrian Leach |Peter Winskill |Azra C Ghani |Austin Burt

AbstractGene drives are a promising means of malaria control with the potential to cause sustained reductions in transmission. In real environments, however, their impacts will depend on local ecological and epidemiological factors. We develop a data-driven model to investigate the impacts of gene drives that causes vector population suppression.

Apr 9, 2024 | biorxiv.org | Penelope A. Hancock |Adrian Leach |Peter Winskill |Azra C Ghani

AbstractGene drive technologies are a promising means of malaria control with the potential to cause widespread and sustained reductions in transmission. In real environments, however, gene drive impacts will depend on local ecological and epidemiological factors. We develop a data-driven model to investigate the impacts of a gene drive that causes vector population suppression.

Sep 14, 2023 | nature.com | Peter Winskill |Amani Thomas Mori

AbstractSevere malarial anaemia can be fatal if not promptly treated. Hospital studies may under-represent the true burden because cases often occur in settings with poor access to healthcare. We estimate the relationship of community prevalence of malaria infection and severe malarial anaemia with the incidence of severe malarial anaemia cases in hospital, using survey data from 21 countries and hospital data from Kenya, Tanzania and Uganda.

Jul 19, 2023 | nature.com | Daniela Olivera Mesa |Jaspreet Toor |Oliver Watson |Peter Winskill |Gregory Barnsley |David Khoury | +2 more

DataWe used empirical estimates of vaccine effectiveness against what we term mild disease (positive polymerase chain reaction (PCR) tests including symptomatic cases and asymptomatic infections detected through screening in schools and workplaces), hospitalisations (defined as admission recorded in the Emergency Care Dataset within 14 days of a positive test) and death (within 28 days of a positive test) with the Delta and Omicron BA.1/BA.2 variants from England.