Pharmacogenetic Unit

Jul 1, 2024 | onlinelibrary.wiley.com | Laura Agulló |Pharmacogenetic Unit |Mónica Escorial |Samantha Orutño

1 INTRODUCTION Opioid use disorder (OUD) affects millions of chronic non cancer pain (CNCP) people worldwide1 and requires the evaluation of different biological variables, including sex.2 Findings from the literature suggest that women are more likely to use prescription opioids3 with faster progression of abuse after their first substance use, unlike men who show higher overdose death rates.4 Taking into account the higher chronic pain prevalence in older women,5 the socio-cultural...