Philip Chiu-Tsun Tang

Jan 5, 2024 | onlinelibrary.wiley.com | Philip Chiu-Tsun Tang |Max Chan |Jeff Chung |Alex Chan

Graphical Abstract Macrophage–Myofibroblast Transition In article number 2302203, Philip Chiu-Tsun Tang, Max Kam-Kwan Chan, Patrick Ming-Kuen Tang, and co-workers, elucidated dynamics of cancer-associated fibroblast (CAF) with integrative bioinformatics at single-cell resolution, therefore unexpectedly identified the importance of a hematopoietic mediator RUNX1 (phosphorylated Runx1, red) for macrophage–myofibroblast transition (MMT) in lung cancer, which may represent a druggable target for...

Nov 15, 2023 | onlinelibrary.wiley.com | Philip Chiu-Tsun Tang |Max Chan |Jeff Chung |Alex Chan

1 Introduction Lung carcinoma is a major cause of death worldwide. There were 5422 new cases of lung cancer in 2020 and ranked as the top cause of cancer deaths in 2020 in Hong Kong (Hong Kong Cancer Registry). Surgery, chemotherapy, and radiotherapy have been the mainstays of treatment for decades.