Phillip J. Bergen

Oct 5, 2023 | onlinelibrary.wiley.com | Benjamin W. Muir |Phillip J. Bergen |Xiangfeng Lai |Seong Hoong Chow

1 Introduction A global infectious disease crisis is looming due to the emergence and dissemination of multidrug-resistant (MDR) Gram-negative bacteria.[1] Klebsiella pneumoniae, Acinetobacter baumannii, and Pseudomonas aeruginosa are key Gram-negative members of the ESKAPE pathogens that are progressively becoming resistant to last-line antibiotics such as polymyxins.[2] Among these Gram-negative bacteria, hypervirulent K.