-
Jan 12, 2025 | 
academic.oup.com | Biocomputing Group |Pier Luigi
The knowledge of protein stability upon residue variation is an important step for functional protein design and for understanding how protein variants can promote disease onset. Computational methods are important to complement experimental approaches and allow a fast screening of large datasets of variations. In this work we present DDGemb, a novel method combining protein language model embeddings and transformer architectures to predict protein ΔΔG upon both single- and multi-point variations.
-
Dec 4, 2024 | 
mdpi.com | Aldo Tagliani |Novi Inverardi |Pier Luigi
1. Introduction and Some Useful ToolsThe random variable X follows the lognormal distribution with parameters μ ∈ R and σ 2 > 0 , say X ∼ L N ( μ , σ 2 ) , if X is absolutely continuous with values in R + and has density function L N ( x ) = 1 2 π σ 2 x e − 1 2 σ 2 ( ln ( x ) − μ ) 2 , x ≥ 0 , (1) with integer moments μ k = e k μ + 1 2 k 2 σ 2 for k = 1 , 2 , ⋯ .
-
Nov 25, 2024 | 
zenodo.org | De Leo |Pier Luigi |La Forgia |Maria Teresa
Funded by the ELIXIRxNextGenIT the ELIXIRxNextGenIT project (PNRR IR0000010) and the ELIXIR Node Industry Engagement Days Pilot Programme, “ELIXIR-IT: A Bridge Between Research and Biotechnology Industry” was organized by the Italian node of ELIXIR (Europe’s leading infrastructure for life sciences research) in collaboration with Italbiotec and Confindustria Bari-Bat.
-
Nov 12, 2024 | 
arxiv.org | Pier Luigi
-
Oct 29, 2024 | 
dialnet.unirioja.es | Pier Luigi |Pier Luigi Tucci
IdiomacatalàDeutschEnglishespañoleuskarafrançaisgalegoitalianoportuguêsromână
-
Oct 17, 2024 | 
mdpi.com | Pier Luigi Surico |Pier Luigi |Marcus G. Kohnstam |Zhonghui K. Luo
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
-
Sep 10, 2024 | 
frontiersin.org | Pier Luigi |Maria Pia
OPINION article Front. Neurosci., 10 September 2024 This article is part of the Research Topic Reviews and Perspectives in Neuromorphic Engineering: Novel Neuromorphic Computing Approaches View all 7 articles
1 Introduction
The UN General Assembly (2015) has compiled an Agenda, containing 17 goals to be pursued worldwide to promote a sustainable future by 2030.
-
Jul 17, 2024 | 
bmccancer.biomedcentral.com | Pier Luigi
We used a two-sample MR analysis to investigate the causal relationships between 41 inflammatory cytokines (Supplementary Data S1) and endometrial cancer from the GWAS of Finns and 17 cohorts [25, 26]. The inverse variance weighted (IVW) test with random effects was applied for the primary analysis process to estimate the causal effect of inflammatory cytokines and endometrial cancer [27]. Four additional MR models were performed as supplementary methods [28,29,30].
-
Jun 3, 2024 | 
karger.com | Pier Luigi
This content is only available via PDF.
This work is licensed under a
Creative Commons Attribution-NonCommercial 4.0 International License
.
-
May 20, 2024 | 
advancesinsimulation.biomedcentral.com | Pier Luigi |Perioperative Care |Francisco Maio
Simulation plays a pivotal role in addressing universal healthcare challenges, reducing education inequities, and improving mortality, morbidity and patient experiences. It enhances healthcare processes and systems, contributing significantly to the development of a safety culture within organizations. It has proven to be cost-effective and successful in enhancing team performance, fostering workforce resilience and improving patient outcomes.
