Ping Gao

Jan 25, 2025 | onlinelibrary.wiley.com | Ping Gao

1 Introduction The objective of a randomized clinical trial is to demonstrate that a new treatment has superior efficacy than a control. In a typical trial design, an assumed effect size, that is, the magnitude of the difference in an efficacy endpoint between the new treatment and the control, is often used to calculate a sample size that provides a target unconditional power for rejecting the null hypothesis of no efficacy.

Nov 27, 2024 | cell.com | HUI LU |Huiya Liu |Ronghui Yan |Wenhao Ma |Haiying Liu |Rui Liu | +5 more

Keywords Sorafenib resistance Hepatocellular carcinoma HCC organoids Intracellular pH homeostasis CA2 Research topic(s) CP: Cancer Introduction Liver cancer is the sixth most prevalent cancer globally, resulting in over 800,000 deaths in 2020.1 Hepatocellular carcinoma (HCC) constitutes approximately 90% of primary liver cancer cases.2 The absence of reliable markers for the early HCC detection leads to a significant proportion of patients being diagnosed at advanced stages, precluding...

Oct 12, 2023 | chemistry-europe.onlinelibrary.wiley.com | Ning Liu |Ping Gao |Hai-Yan Lu |Lei Fang

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