Pramit Khetrapal

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Comparing biparametric to multiparametric MRI in the diagnosis of clinically significant prostate cancer in biopsy-naive men (PRIME): a prospective, international, multicentre, non-inferiority within-patient, diagnostic yield trial protocol

Apr 6, 2023 | bmjopen.bmj.com | Aqua Asif |Arjun Nathan |Alexander Ng |Pramit Khetrapal

Reporting of MRIPatients will undergo (or will have undergone) standard of care mpMRI as per their local protocol. The radiologists participating in this trial will be blinded to the DCE sequences and will report the MRI using only the biparametric (T2W and DWI) sequences in report 1. After reporting the bpMRI, the same radiologist will be unblinded to the DCE sequences and will re-report the MRI using the mpMRI sequences (T2W, DWI and DCE) in report 2 (figure 1).

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