Qianyu Shi

May 31, 2024 | onlinelibrary.wiley.com | Qianyu Shi |Wei Guo |Tao Ji |Xiaodong Tang

1 INTRODUCTION The prognosis of pelvic bone sarcomas is notably inferior when compared to those occurring in extremities.1-5 Surgical excision is the principal therapeutic intervention for pelvic bone sarcomas, with R0 resection representing a potentially curative option capable of significantly enhancing prognosis.6 However, the technical challenge of achieving R0 resection is compounded by the complex anatomic relationships with vital organs, major vessels, and nerves in the pelvic...

May 27, 2023 | nature.com | Qianyu Shi |Peng Zhang

AbstractTumor thrombus of bone sarcomas represents a unique reservoir for various types of cancer and immune cells, however, the investigation of tumor thrombus at a single-cell level is very limited. And it is still an open question to identify the thrombus-specific tumor microenvironment that is associated with the tumor-adaptive immune response.