Qing Lan

Nov 18, 2024 | nature.com | Erping Long |Jinhu Yin |Xinti Sun |Younghun Han |Jinyoung Byun |Tongwu Zhang | +6 more

Correction to: Nature Communications https://doi.org/10.1038/s41467-024-52356-9, published online 12 September 2024The original version of the Supplementary Information associated with this Article included an incorrect Supplementary Data 1-18 file, in which specific legends for each Supplementary Data table were missing. The HTML has been updated to include a corrected version of Supplementary Data 1-18.

Sep 11, 2024 | nature.com | Erping Long |Jinhu Yin |Xinti Sun |Younghun Han |Jinyoung Byun |Tongwu Zhang | +6 more

AbstractGenome-wide association studies (GWAS) identified over fifty loci associated with lung cancer risk. However, underlying mechanisms and target genes are largely unknown, as most risk-associated variants might regulate gene expression in a context-specific manner. Here, we generate a barcode-shared transcriptome and chromatin accessibility map of 117,911 human lung cells from age/sex-matched ever- and never-smokers to profile context-specific gene regulation.

Aug 27, 2024 | thelancet.com | Qing Lan |Long Guo

1 The burden of cardiovascular disease and risk for subsequent major adverse cardiovascular events in survivors of childhood cancer: a prospective, longitudinal analysis from the St Jude Lifetime Cohort Study. We are deeply interested in the study by Rawan A Hammoud and colleagues,and offer them our heartfelt congratulations.

Aug 7, 2024 | mdpi.com | Pengyu Wang |Qing Lan |Qi Huang |Ruyi Zhang

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Jul 22, 2024 | nature.com | Ji Wang |Qing Lan

AbstractInvasion and migration are the key hallmarks of cancer, and aggressive growth is a major factor contributing to treatment failure and poor prognosis in glioblastoma. Protein arginine methyltransferase 6 (PRMT6), as an epigenetic regulator, has been confirmed to promote the malignant proliferation of glioblastoma cells in previous studies. However, the effects of PRMT6 on glioblastoma cell invasion and migration and its underlying mechanisms remain elusive.