Qinghua Wang

Aug 24, 2024 | dovepress.com | Haopeng Li |Juan Zhou |Qinghua Wang |Yaru Zhu

Introduction Sepsis 3.0 defines sepsis as a syndrome characterized by life-threatening organ dysfunction caused by a dysregulated host response to infection.1 Previously, the diagnosis of urosepsis was primarily based on the presence of urinary tract infection (UTI) evidence combined with the fulfillment of at least two criteria of the systemic inflammatory response syndrome (SIRS).2 With the update of recent guidelines,3,4 the diagnostic criteria for urosepsis now require a Sequential Organ...

Aug 5, 2024 | preprints.org | Qinghua Wang

PreprintReviewVersion 1This version is not peer-reviewedVersion 1: Received: 2 August 2024 / Approved: 2 August 2024 / Online: 5 August 2024 (09:32:38 CEST)Prud'homme, G. J.; Wang, Q. Anti-Inflammatory Role of the Klotho Protein and Relevance to Aging. Preprints 2024, 2024080213. https://doi.org/10.20944/preprints202408.0213.v1Prud'homme, G. J.; Wang, Q. Anti-Inflammatory Role of the Klotho Protein and Relevance to Aging. Preprints 2024, 2024080213.

Oct 9, 2023 | nature.com | Qinghua Wang

AbstractCryo-electron microscopy (cryo-EM) captures snapshots of dynamic macromolecules, collectively illustrating the involved structural landscapes. This provides an exciting opportunity to explore the structural variations of macromolecules under study. However, traditional cryo-EM single-particle analysis often yields static structures. Here we describe OPUS-DSD, an algorithm capable of efficiently reconstructing the structural landscape embedded in cryo-EM data.