Qingrong Li

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Open architecture of archaea MCM and dsDNA complexes resolved using monodispersed streptavidin affinity CryoEM - Nature Communications

Nov 26, 2024 | nature.com | Gangshun Yi |Mingda Ye |Yuewen Sheng |Ying Lu |Ming Li |Qingrong Li | +1 more

AbstractThe cryo-electron microscopy (cryoEM) method has enabled high-resolution structure determination of numerous biomolecules and complexes. Nevertheless, cryoEM sample preparation of challenging proteins and complexes, especially those with low abundance or with preferential orientation, remains a major hurdle.

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