Rachel Done

Jun 28, 2024 | biorxiv.org | Joshua Robertson |Joanna B. Goldberg |Rachel Done |Samatha Prezioso

AbstractThe opportunistic pathogen Pseudomonas aeruginosa causes debilitating lung infections in people with cystic fibrosis, as well as eye, burn, and wound infections in otherwise immunocompetent individuals. Many of P. aeruginosa's virulence factors are regulated by environmental changes associated with human infection, such as a change in temperature from ambient to human body temperature. One such virulence factor is protease IV (PIV).