Rafael González-Manzanares

Jan 7, 2025 | onlinelibrary.wiley.com | Ignacio Martín Gallo |Lorenzo Azzalini |Rafael González-Manzanares |Silvia Moscardelli

1 Introduction Coronary artery disease is currently the most frequent cause of heart failure and left ventricular dysfunction [1]. Coronary artery bypass grafting (CABG) is the revascularization technique of choice for patients with complex coronary anatomy and left ventricular ejection fraction (LVEF) < 35% [2, 3]. However, percutaneous revascularization may be considered in selected patients with angina and high risk for CABG or in those patients who refuse surgery [4].

Aug 16, 2024 | mdpi.com | Consuelo Fernández-Avilés |Rafael González-Manzanares |Soledad Ojeda |Juan Castillo

All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.

Jul 25, 2024 | mdpi.com | Francisco Hidalgo |Rafael González-Manzanares |Ignacio Martín Gallo |Marco Alvarado

All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.

Oct 26, 2023 | mdpi.com | Gloria Heredia |Rafael González-Manzanares |Soledad Ojeda |José Molina

1. IntroductionAcute lymphoblastic leukemia (ALL) is the most prevalent type of cancer in the pediatric population. Over the past few decades, anthracycline-based therapies have significantly improved survival rates in these patients [1]. However, due to the exposition to cardiotoxic agents, childhood leukemia survivors (CLS) have an increased risk of cardiovascular disease during their lifetimes [2].

Sep 20, 2023 | mdpi.com | Jorge Perea-Armijo |José López-Aguilera |Rafael González-Manzanares |Cristina Pericet-Rodriguez

1. IntroductionHeart failure (HF) is a syndrome whose prevalence has been increasing in recent decades due to an increase in diagnoses and improved survival due to new therapeutic strategies [1]. Patients with heart failure with reduced ejection fraction (HFrEF) in the chronic phase are in a phase of apparent clinical stability, and despite pharmacological advances that have improved prognoses, these patients have a significant residual risk of clinical deterioration and mortality [1,2].