Rebecca L. Schill

Sep 30, 2023 | cell.com | Byung Chul Jung |Rebecca L. Schill |Katherine Fabrizio MA

Highlights•TET3 is necessary for full adipogenesis in vivo•TET3 is necessary for diet-induced unhealthy adipose expansion•Reduced adipogenesis by the loss of TET3 in APCs leads to enhanced whole-body metabolism•TET3 regulates a set of APC target genes by modulating their DNA methylation profileSummaryMaintaining healthy adipose tissue is crucial for metabolic health, requiring a deeper understanding of adipocyte development and response to high-calorie diets.