Richard Gawel

New York

Online Managing Editor at Healio

Online Managing Editor at Healio Allergy/Asthma

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Articles

Afternoon inhaler doses associated with better asthma control

1 week ago | healio.com | Richard Gawel

Key takeaways: Patients had better improvements in their FEV1 percent predicted and FEV1/FVC ratio with afternoon doses. Patients also saw larger overnight reductions in blood eosinophil counts with afternoon doses. Patients with asthma experienced higher FEV1 and lower blood eosinophil counts when they used a single dose of beclomethasone dipropionate in the afternoon compared with other dosing regimens, according to a study published in Thorax.
Vaccination guidelines vary for immunocompromised patients

1 week ago | healio.com | Richard Gawel

Key takeaways:Influenza, pneumococcal, zoster and COVID-19 vaccines all are recommended for immunocompromised patients. Vaccines may be less effective when patients get them during immunosuppressive treatment. Patients who are immunocompromised still can receive a variety of vaccinations based on their specific needs, Cassandra Calabrese, DO, saidduring her presentationat Updates in Primary Immunodeficiency 2025.
Health care systems tap AI to screen populations for primary immunodeficiencies

1 week ago | healio.com | Richard Gawel

Key takeaways:Artificial intelligence can scan electronic health records for risk factors indicating potential primary immunodeficiencies. These systems can accelerate diagnoses of primary immunodeficiencies by 3 years. Artificial intelligence can improve care for patients with primary immunodeficiencies, but human input is still necessary, Nicholas L. Rider, DO, saidat Updates in Primary Immunodeficiency 2025.
Sequencing identifies specific milk protein causing eosinophilic esophagitis

2 weeks ago | healio.com | Richard Gawel

Key takeaways: The patient had a clinically established eosinophilic esophagitis milk allergy. Conventional T cells that expressed eoeTCR-4 proliferated when researchers stimulated them with recombinant beta-casein. Gene sequencing enabled researchers to identify the specific milk protein that triggered a patient’s eosinophilic esophagitis, according to a study published in The Journal of Allergy and Clinical Immunology.
Black patients with allergic rhinitis see fewer prescriptions for sublingual immunotherapy

2 weeks ago | healio.com | Richard Gawel

While racial disparities in SLIT prescribing are unfortunately probably to be expected given broader health care inequities that are commonly uncovered, this study also highlights another issue that may further hinder SLIT access to patients who could benefit from SLIT — the extremely low overall prescription rate of SLIT for allergic rhinitis patients.
Sublingual epinephrine outcomes fall between manual injection, autoinjectors

3 weeks ago | healio.com | Richard Gawel

Key takeaways: Recommendations for outcomes that fall between results with manual injection and autoinjectors come from the FDA. “Bracketed” outcomes included geometric mean peak exposure and time to maximum concentration. Sublingual delivery of epinephrine achieved pharmacokinetic and pharmacodynamic results that were comparable with manual intramuscular injection and autoinjectors, according to a study published in Annals of Allergy, Asthma & Immunology.
Children, adolescents see fewer monthly migraine, headache days with fremanezumab

3 weeks ago | healio.com | Richard Gawel

Key takeaways: Fremanezumab targets calcitonin gene-related peptides. The placebo group had one more migraine and headache day each month. The safety profiles for the treatment and placebo groups were similar. SAN DIEGO — Children and adolescents treated with fremanezumab experienced fewer migraine and headache days compared with placebo, according to an abstract presented at the American Academy of Neurology Annual Meeting.
Federal health cuts expected to harm asthma patients

3 weeks ago | healio.com | Richard Gawel

Key takeaways: The National Asthma Control Program and Office on Smoking and Health have been shut down. Research funding has been cut, and changes to Medicare and Medicaid have been proposed. As the federal government lays off workers at CDC and NIAID, shutters programs, cuts research grants, and considers changes in Medicaid and Medicare, asthma patients will experience worse outcomes, according to experts.
Oral immunotherapy for hazelnut allergy does not yield other tree nut desensitization

3 weeks ago | healio.com | Richard Gawel

Key takeaways: 96.7% of the treatment group and 14.3% of the control group achieved desensitization to hazelnut. Most patients who also had walnut and cashew allergy did not see any changes in those reaction thresholds. Hazelnut oral immunotherapy was safe and effective, but cross-desensitization for patients who also had walnut and cashew allergy was unlikely, according to a study published in The Journal of Allergy and Clinical Immunology: In Practice.
Consensus report defines anaphylaxis, provides clinical support tool

4 weeks ago | healio.com | Richard Gawel |Kristen Dowd |David B.K. Golden

I highly commend the authors for conceptualizing and executing the development of this consensus document. Although largely evidence based, it does incorporate the perceptions of patient advocates and other stakeholders. This provides an improved framework for clinicians and patients.