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1 week ago | 
healio.com | Erik Swain |Richard Smith |Maria A. Pabon
Key takeaways: Finerenone reduced risk for new-onset atrial fibrillation vs. placebo in a pooled analysis. The patient population included those with certain kinds of heart failure and those with diabetic kidney disease. CHICAGO — Finerenone prevented new-onset atrial fibrillation or flutter in patients with chronic kidney disease and type 2 diabetes or heart failure with mildly reduced or preserved ejection fraction, according to new data from FINE-HEART.
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1 week ago | 
healio.com | Erik Swain |Richard Smith
Key takeaways:A transcatheter aortic valve replacement system designed to treat aortic regurgitation exceeded its safety and performance goals. A randomized controlled trial comparing TAVR with surgery is planned. CHICAGO — For patients with symptomatic aortic regurgitation at high surgical risk, a transcatheter aortic valve replacement system exceeded safety and performance goals, according to results of the ALIGN-AR trial.
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1 week ago | 
healio.com | Michael Monostra |Richard Smith
Key takeaways: Multiple predictors were linked to biochemical or structural evidence of disease 1 year after papillary thyroid microcarcinoma diagnosis. Risk stratification should be used to guide management of small tumors. Rather than tumor size alone, the American Thyroid Association’s risk stratification system should be used when assessing papillary thyroid microcarcinomas, according to data published in The Journal of Clinical Endocrinology & Metabolism.
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1 week ago | 
healio.com | Scott Buzby |Richard Smith |Garima Sharma
Key takeaways: Adverse pregnancy outcomes do not entirely explain the link between prepregnancy obesity and CVD risk. Weight management before pregnancy may reduce excess risk for heart disease. Gestational diabetes and hypertensive disorders of pregnancy mediated only a small part of the association between women’s midlife heart health and prepregnancy obesity, researchers reported.
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1 week ago | 
healio.com | Michael Monostra |Richard Smith |Richard M. Bergenstal
Key takeaways: Adults with type 2 diabetes lowered their HbA1c from 8.18% at baseline to 7% at 26 weeks with insulin icodec plus a CGM. Time in range improved by more than 20 percentage points during the study. Once-weekly basal insulin combined with an intermittently scanned continuous glucose monitor reduced HbA1c and improved time in range for adults with type 2 diabetes, researchers reported.
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1 week ago | 
healio.com | Shawn M. Carter |Richard Smith
Key takeaways:Researchers found a notable interaction based on patients' prior history of kidney stones. Hypokalemia was more common for patients on chlorthalidone regardless of stone history. BOSTON — Long-acting diuretic chlorthalidone may increase the risk for kidney stones in adults who have previously had them, according to findings presented at the National Kidney Foundation Spring Clinical Meetings.
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1 week ago | 
healio.com | Jill Rollet |Richard Smith |Shalabh Gupta
Key takeaways:Of survey respondents, 47% said large number and large size of pills were among top phosphate binder adherence barriers. An investigational agent is smaller, swallowed whole and dosed with fewer pills. BOSTON — Patients on kidney dialysis reported better adherence to an investigational phosphate-binding agent designed to be smaller, swallowed whole and dosed with fewer pills than available oral therapies, according to survey data.
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1 week ago | 
healio.com | Shawn M. Carter |Richard Smith
Key takeaways:The NKF continues to support policies aimed at prevention, detection and access. NKF has educated 15,000 individuals and supported 7,000 people with mentorships. BOSTON — The National Kidney Foundation Spring Clinical Meetings opened its 75th annual event with a clear message: Enhance patient care by advancing awareness.
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2 weeks ago | 
healio.com | Jill Rollet |Richard Smith |Chee Kay Cheung
Key takeaways: At some point during the first 24 weeks, 58% of participants had complete remission of proteinuria. Mean urine protein creatinine ratio declined by 61.9% at week 4 and by 68.9% at week 24. BOSTON — Adults recently diagnosed with immunoglobulin A nephropathy who were assigned sparsentan as first-line therapy experienced rapid and sustained reductions in proteinuria, according to researchers.
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2 weeks ago | 
healio.com | Erik Swain |Richard Smith |Matthew J. Budoff
Key takeaways: For patients with stable coronary artery disease, colchicine conferred lower total plaque volume as measured by coronary CT angiography vs. placebo. There was no effect on volume of low attenuation plaque. CHICAGO — Among patients with stable coronary artery disease, colchicine lowered total plaque volume compared with placebo but had no impact on low attenuation plaque volume, researchers reported.
