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Nov 27, 2024 | 
thetransmitter.org | Anne West |Megan Peters |Robert C. Froemke |Steve Ramirez
Answers have been edited for length and clarity. What paper changed your life? Histone demethylation mediated by the nuclear amine oxidase homolog LSD1. Shi Y., Lan F., Matson C., Mulligan P., Whetstine J.R., Cole P.A., Casero R.A. and Yang S. Cell (2004)In this paper, Yang Shi and his colleagues reported the first histone demethylase—an enzyme that removes methyl groups from chromatin to regulate DNA transcription—which they named lysine-specific demethylase 1 (LSD1).
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Oct 16, 2024 | 
thetransmitter.org | Megan Peters |Robert C. Froemke |Steve Ramirez |Jason Shepherd
Answers have been edited for length and clarity. What paper changed your life?: Spontaneous cortical activity reveals hallmarks of an optimal internal model of the environment. Berkes P., Orbán G., Lengyel M. and Fiser J. Science (2011)Many dominant opinions in neuroscience hold that, when it comes to perception, the brain operates by performing something that looks like Bayesian inference.
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Sep 17, 2024 | 
thetransmitter.org | Jill Adams |Rachel Zamzow |Robert C. Froemke |Angie Voyles Askham
Here is a roundup of autism-related news and research spotted around the web for the week of 16 September. Contributing writer Share this article: Tags: Spectrum, Autism, Science and society, Spotted Mice missing one or both copies of the gene CDKL5, which causes CDKL5 deficiency disorder in people, display autism-like traits as early as 2 weeks of age.
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Sep 17, 2024 | 
thetransmitter.org | Robert C. Froemke |Steve Ramirez |Jill Adams |Angie Voyles Askham
Answers have been edited for length and clarity. What paper changed your life?: Response of hippocampal synapses to natural stimulation patterns. L.E. Dobrunz and C.F. Stevens Neuron (1999)Lynn Dobrunz and Charles Stevens described how natural stimulus patterns from in-vivo recordings can trigger synaptic plasticity when applied to hippocampal slices in vitro.
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Sep 9, 2024 | 
thetransmitter.org | Samuel J. Gershman |Daniel Aharoni |Robert C. Froemke |Rachel Zamzow
This series of scientist-written essays explores the benefits and challenges of data-sharing and open-source technologies in neuroscience. The field of neuroscience has witnessed a sea change in its attitude toward open science over the past 10 years. Thanks to mandates from journals and funders, the establishment of large-scale public repositories, and broader shifts in academic culture, it is now routine for many researchers to deposit data for use by anyone, anywhere.
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Jul 15, 2024 | 
thetransmitter.org | Letisha Wyatt |Daniel Aharoni |Robert C. Froemke |Mark Laubach
Data-handling and data-sharing are an essential part of the research endeavor, yet most trainees learn how to do it through trial and error. Before I went to graduate school, I worked at a contract research organization supporting data management and sharing for clinical trials across the United States.
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May 8, 2024 | 
thetransmitter.org | Lauren Schenkman |Jill Adams |Robert C. Froemke
Repeated exposure to cocaine and morphine subverts the reward-system neurons that underlie hunger and thirst, according to a new study in mice. “The nerve cells get scrambled at the neural level in terms of their responses to food and water,” says lead investigator Eric Nestler, professor of neuroscience at the Icahn School of Medicine at Mount Sinai.
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May 7, 2024 | 
thetransmitter.org | Elissa Welle |Jill Adams |Robert C. Froemke
ReporterThe Transmitter Share this article: Tags: Sensory systems, Drosophila, Motor behavior, Motor skills, sensorimotor As a former acrobat and circus performer, Eugenia Chiappe is quick to appreciate the performance skills of her research model, Drosophila melanogaster: The fruit flies gracefully pitter-patter atop a tiny stage in her lab and swivel and dive in flight—all signs of a nervous system evolved for just such sophisticated feats of locomotion.
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May 7, 2024 | 
thetransmitter.org | Jill Adams |Elissa Welle |Robert C. Froemke
Welcome to The Transmitter Spectrum is now a key section of The Transmitter and continues to publish news and perspectives about autism research. Previous Spectrum articles are available at thetransmitter.org.
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May 6, 2024 | 
thetransmitter.org | Robert C. Froemke |Grace Lindsay |Angie Voyles Askham
Have you seen “Planet Earth II”? Specifically, the scene in which a sloth swims among island mangrove trees in search of a friend? I often mention this video when talking to graduate students or recruits to my lab because, for me, it prompts so many questions: How good is sloth hearing? What sorts of vocalizations do they respond to and produce? How does a sloth learn to swim? Is it an innate behavior, or do sloth parents teach their babies how to swim, like otter parents do?
