Robert Neumar

Jun 23, 2024 | onlinelibrary.wiley.com | Alexander T. Janke |Robert Neumar

Corresponding Author Alexander T. Janke MD, MHS, MSc Department of Emergency Medicine, University of Michigan, Ann Arbor, Michigan, USA Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, Michigan, USA Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, Michigan, USA Correspondence Alexander T. Janke, Department of Emergency Medicine, University of Michigan, Ann Arbor, MI 48109, USA. Email: [email protected] for more papers by this author

Jun 6, 2024 | nature.com | Robert Neumar

AbstractExtracorporeal cardiopulmonary resuscitation (ECPR) is emerging as a feasible and effective rescue strategy for prolonged cardiac arrest (CA). However, prolonged total body ischemia and reperfusion can cause microvascular occlusion that prevents organ reperfusion and recovery of function. One hypothesized mechanism of microvascular “no-reflow” is leukocyte adhesion and formation of neutrophil extracellular traps.