Robin Meyers

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Articles

DDX50 cooperates with STAU1 to effect stabilization of pro-differentiation RNAs

Jan 6, 2025 | cell.com | Weili Miao |Douglas Porter |Zurab Siprashvili |Ian Ferguson |Luca Ducoli |Duy Nguyen | +11 more

Keywords RNA helicase DDX50 tissue differentiation glucose STAU1 mRNA stability Research topic(s) CP: Molecular biology Introduction RNA-binding proteins (RBPs) can promote either RNA stability or decay to mediate post-transcriptional control of RNA expression in ways important for cell fate.1,2 The DExD/H-box RNA helicases comprise a family of RBPs that exert diverse impacts on RNA, including on RNA translation, folding, and subcellular localization,3 but their impacts on RNA stability are...
DDX50 cooperates with STAU1 to effect stabilization of pro-differentiation RNAs

Jan 6, 2025 | cell.com | Weili Miao |Douglas Porter |Zurab Siprashvili |Ian Ferguson |Luca Ducoli |Duy Nguyen | +11 more

Keywords RNA helicase DDX50 tissue differentiation glucose STAU1 mRNA stability Research topic(s) CP: Molecular biology Introduction RNA-binding proteins (RBPs) can promote either RNA stability or decay to mediate post-transcriptional control of RNA expression in ways important for cell fate.1,2 The DExD/H-box RNA helicases comprise a family of RBPs that exert diverse impacts on RNA, including on RNA translation, folding, and subcellular localization,3 but their impacts on RNA stability are...
Disease-Linked Regulatory DNA Variants and Homeostatic Transcription Factors in Epidermis

Nov 11, 2024 | biorxiv.org | Douglas Porter |Robin Meyers |Weili Miao |David Reynolds

AbstractHow transcription factors (TFs) regulate stem cells to maintain homeostasis, how noncoding single nucleotide variants (SNVs) linked to polygenic disease risk relate to such TFs, and the target genes SNVs dysregulate are central questions in stem cell and polygenic disease research. Massively parallel reporter gene analysis (MPRA) of 3,451 SNVs linked to risk for prevalent human skin diseases identified 355 differentially active SNVs (daSNVs).
irCLIP-RNP and Re-CLIP reveal patterns of dynamic protein associations on RNA

Sep 28, 2024 | biorxiv.org | Luca Ducoli |Brian J. Zarnegar |Douglas Porter |Robin Meyers

AbstractRNA binding proteins (RBPs) control varied processes, including RNA splicing, stability, transport, and translation1-3. Dysfunctional RNA-RBP interactions contribute to the pathogenesis of human disease1,4,5, however, characterizing the nature and dynamics of multiprotein assemblies on RNA has been challenging.
Israel's 9/11

Nov 5, 2023 | okgazette.com | Robin Meyers

In the unfolding horror of the last three weeks, many Israelis have called the horrific attack from Hamas “Israel’s 9/11.” If that’s true, let’s hope they handle it better than we did. Unfortunately, it looks like they will not. In fact, it looks like they are following our playbook of revenge, wanton destruction, and political grandstanding perfectly. We know how our post-9/11 misadventures turned out.
Violence begets violence

Oct 8, 2023 | okgazette.com | Robin Meyers

Word came this morning that Palestinian militants launched the largest surprise attack on Israel since Yun Kippur in 1973 and the two sides are now at war. More than 2,000 rockets have been launched into Israel, and communities bordering the Gaza Strip have been invaded and occupied. By the time you read this, Israel will have responded with the most devastating blow to Palestine in its history.
Is God a Christian nationalist?

Sep 24, 2023 | okgazette.com | Robin Meyers

The rhetorician Kenneth Burke is best known for his theories of human communication as drama, but perhaps his most famous quote is about the essence of the human species itself. This is pre-inclusive language, but otherwise it’s a masterpiece: Man is the symbol-using, symbol-making, symbol-misusing animal, inventor of the negative, separated from his natural condition by instruments of his own making, goaded by the spirit of hierarchy, and rotten with perfection.
No wonder people hate religion

Sep 10, 2023 | okgazette.com | Robin Meyers

I have spent my life working on the inside of organized religion, even though my love/hate relationship with most God-talkers makes me an outsider. A quick reminder for those who still go to church: Jesus was permanently — and lethally — on the outside of the religion of his time, and his denunciations of its hypocrisy and misplaced fervor was legendary. “Hypocrites,” (mask-wearing actors) and a “brood of vipers” comes to mind.
No taxation for indoctrination

Aug 27, 2023 | okgazette.com | Robin Meyers

When Oklahoma makes national news, it is often an embarrassment. Now it is alsodangerous. The state’s virtual charter school board has approved on a 3-2 vote (thanks to alast-minute appointment by Gov. Kevin Stitt that guaranteed passage), to establish the firstpublicly-funded religious charter school in the United States. Gov.
The tyranny of screens

Aug 2, 2023 | okgazette.com | Robin Meyers

I recently ran across an amazing article in the New York Times that confirms much of my growing ambivalence about teaching in a world of glowing rectangles. It was entitled, “Why Universities Should Be More Like Monasteries,” by Molly Worthen, a historian at the University of North Carolina who writes about higher education. In it, she details a radical idea whose time has come.