Robin Wilson

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Hyperinsulinemia-induced upregulation of adipocyte TPH2 contributes to peripheral serotonin production, metabolic dysfunction, and obesity

5 days ago | jci.org | Brian Park |Andrew Reeves |Ying Zhu |Robin Wilson

ResearchEndocrinologyMetabolismOpen Access | 10.1172/JCI190765 J Clin Invest. https://doi.org/10.1172/JCI190765. Copyright © 2025, Park et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. View PDF AbstractTryptophan hydroxylase (TPH) is a rate-limiting enzyme for serotonin or 5-hydroxytryptamine (5-HT) synthesis.

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