Ruochi Zhang

Sep 16, 2024 | nature.com | Ruochi Zhang |Jian Ma

Correction to: Nature Methods https://doi.org/10.1038/s41592-024-02230-9, published online 8 April 2024.

Apr 8, 2024 | nature.com | Ruochi Zhang |Jian Ma

AbstractSingle-cell Hi-C (scHi-C) technologies allow for probing of genome-wide cell-to-cell variability in three-dimensional (3D) genome organization from individual cells. Computational methods have been developed to reveal single-cell 3D genome features based on scHi-C, including A/B compartments, topologically associating domains and chromatin loops.

Oct 2, 2023 | biorxiv.org | Yihe Deng |Ruochi Zhang |Pan Xu |Jian Ma

AbstractHypergraphs are powerful tools for modeling complex interactions across various domains, including biomedicine. However, learning meaningful node representations from hypergraphs remains a challenge. Existing supervised methods often lack generalizability, thereby limiting their real-world applications.