Ruthiran Kugathasan

Aug 3, 2023 | journals.plos.org | Ksenia Sukhova |Maya Moshe |Paul Kellam |Ruthiran Kugathasan |PLOS Pathogens

DMS reveals most polyclonal vaccine sera select for mutations at one or two antigenic sites in spike RBDHaving validated the platform’s ability to identify mAb escape mutants, we next screened the library for escape from polyclonal sera. Blood was collected from 8 healthy adults between 2–4 weeks after their 2nd BNT162b2 vaccine dose (S1 Table).