Ryan Alam

Jul 10, 2023 | chemistry-europe.onlinelibrary.wiley.com | John Keating |Ryan Alam

Abstract Present in a number of small molecule derivatives that display a wide range of biological activities, the dihydropyrrolo[3,4-b]indol-(2H)-one (DHPI) core represents an underexplored heterocyclic scaffold. Given the pharmaceutical potential of the DHPI motif, the development of synthetic methodologies that would facilitate their expedient assembly would be highly desirable.