Saeid Ghavami

Jun 17, 2024 | pharmafocusasia.com | Saeid Ghavami

Traditional medicinal chemistry has focused on single-target drugs, effective for many conditions but inadequate for complex diseases like cancer. Polytherapy tackles this but faces challenges. Multi-Target Directed Ligands (MTDLs) offer a novel approach, targeting multiple disease pathways for enhanced efficacy. Integrating MTDLs with lipidomics shows promise in GB therapy development.

Feb 7, 2024 | biorxiv.org | Nisha Singh |Saeid Ghavami |Prashen Chelikani

AbstractMicrobial dysbiosis is an important trigger in the development of oral diseases. Oral keratinocytes or gingival epithelial cells (GECs) offer protection against various microbial insults. Recent studies suggest GECs expressed higher level of bitter taste receptor 14 (T2R14) compared to other taste receptors and toll-like receptors and acts as innate immune sentinels.

Sep 5, 2023 | mdpi.com | Shahla Shojaei |Saeid Ghavami |Atefeh Zarepour |Leila Pirmoradi

This is an early access version, the complete PDF, HTML, and XML versions will be available soon.