Samantha Thomas

2 months ago | biorxiv.org | Haani Jafri |Samantha Thomas |Rachel Cain |Matthew B. Dalva

AbstractVisualization of the submicron organization of excitatory synapses has revealed an unexpectedly ordered architecture consisting of nanocolumns of synaptic proteins that group into nanomodules which scale in number as spine size increases. How these features are related to synaptic function has remained unclear.

Oct 3, 2023 | cell.com | Alex Colville |Cristina Rodriguez-Mateo |Samantha Thomas |Heather Ishak

Highlights•Death-seq is a screening method that enables the systematic study of cell death•Death-seq enables the identification of enhancers and inhibitors of cell death•CRISPR screens with Death-seq identify senolytics for age-related diseaseSummarySelectively ablating damaged cells is an evolving therapeutic approach for age-related disease.

Sep 11, 2023 | cell.com | Alex Colville |Samantha Thomas |Heather Ishak |Cristina Rodriguez-Mateo

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