Samie R. Jaffrey

Sep 14, 2023 | nature.com | Samie R. Jaffrey

AbstractStress granules are biomolecular condensates composed of protein and mRNA. One feature of stress granule-enriched mRNAs is that they are often longer than average. Another feature of stress granule-enriched mRNAs is that they often contain multiple N6-methyladenosine (m6A) residues. m6A is bound by the YTHDF proteins, creating mRNA–protein complexes that partition into stress granules in mammalian cells.

Aug 21, 2023 | nature.com | Sara Zaccara |Samie R. Jaffrey

Correction to: Nature Reviews Molecular Cell Biology https://doi.org/10.1038/s41580-019-0168-5, published online 13 September 2019. In the version of this article initially published, there were errors in the pseudouridine (Ψ) structure displayed in the lower-right side of the Box 1 figure, including an extra N denoting a N–C glycosyl bond appearing below HN, and a single instead of a double bond appearing at the top O in the figure.

Jun 21, 2023 | nature.com | Xing Li |Samie R. Jaffrey

Cruz, J. A. & Westhof, E. The dynamic landscapes of RNA architecture. Cell 136, 604–609 (2009). Article  CAS  PubMed  Google Scholar  Westhof, E. & Leontis, N. B. An RNA-centric historical narrative around the Protein Data Bank. J. Biol. Chem. 296, 100555 (2021). Article  CAS  PubMed  PubMed Central  Google Scholar  Assmann, S. M., Chou, H. L. & Bevilacqua, P. C. Rock, scissors, paper: how RNA structure informs function. Plant Cell https://doi.org/10.1093/plcell/koad026 (2023). VarnBuhler, B. S., Moon, J., Dey, S.