Samsung Bioepis Co

2 months ago | rxlist.com | John P. Cunha |Samsung Bioepis Co

Description for Xbryk Denosumab-dssb is a human IgG2 monoclonal antibody that binds to human RANKL. Denosumab-dssb has an approximate molecular weight of 147 kDa and is produced in genetically engineered mammalian (Chinese hamster ovary) cells. Xbryk (denosumab-dssb) injection is a sterile, preservative-free, clear, colorless to slightly yellow solution for subcutaneous use.

2 months ago | rxlist.com | John P. Cunha |Samsung Bioepis Co

WARNING SEVERE HYPOCALCEMIA IN PATIENTS WITH ADVANCED KIDNEY DISEASE Patients with advanced chronic kidney disease (eGFR <30 mL/min/1.73 m²), including dialysis-dependent patients, are at greater risk of severe hypocalcemia following denosumab products administration. Severe hypocalcemia resulting in hospitalization, life-threatening events and fatal cases have been reported [see WARNINGS AND PRECAUTIONS].