Samuel Ogunsola

Feb 24, 2024 | biorxiv.org | Ling Liu |Hai Nguyen |Urmi Das |Samuel Ogunsola

AbstractInterval-training activities induce adaptive cellular changes without altering their fundamental identity, but the precise underlying molecular mechanisms are not fully understood. In this study, we demonstrate that interval-training depolarization (ITD) of pituitary cells triggers distinct adaptive or homeostatic splicing responses of alternative exons. This occurs while preserving the steady-state expression of the Prolactin and other hormone genes.