Santosh L. Saraf

Jun 22, 2023 | onlinelibrary.wiley.com | Jin H. Han |Santosh L. Saraf |Victor R. Gordeuk

Abstract Sickle cell disease (SCD) is an immunocompromised condition and patients with SCD may have a reduced immune response to certain vaccinations. The report by Nakahara et al. demonstrated that SCD patients exhibited elevated and more sustained IgG production following COVID-19 vaccination, when compared to healthy controls. This suggests that the immune response to vaccinations may vary among different types of vaccines in individuals with SCD. Commentary on: Nakahara et al.