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  • Nov 7, 2023 | jamanetwork.com | Melissa L. McPheeters |Elizabeth O’Connor |Sean Riley |Sara Kennedy

    Key PointsQuestion  Which pharmacotherapies are associated with improved outcomes for people with alcohol use disorder? Findings  In this systematic review and meta-analysis that included 118 clinical trials and 20 976 participants, 50 mg/d of oral naltrexone and acamprosate were each associated with significantly improved alcohol consumption-related outcomes compared with placebo.

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