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Jan 8, 2025 | 
medschool.duke.edu | Sarah Avery
The only way to ascend a mountain is by putting one foot ahead of the other, one step and then another, over and again. That tenacity took Shelley Hwang, MD, to the top of Mount Kilimanjaro in 2021, the highest mountain in Africa. It’s also led her to the pinnacle of a research quest that began decades ago as a daunting challenge.
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Jan 6, 2025 | 
medicalxpress.com | Sarah Avery
Hospitalized premature infants who received recommended two-month vaccinations had an increased risk of a short episode of apnea, but no serious complications arose, according to a study led by Duke Health researchers. Appearing in the journal JAMA Pediatrics, the study confirms previous findings linking apnea, which is a pause in breathing, to vaccinations among premature babies.
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Nov 21, 2024 | 
msn.com | Sarah Avery
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Nov 21, 2024 | 
medicalxpress.com | Sarah Avery
Building on research that has linked immune responses with certain neurobehavioral conditions, researchers at Duke Health have identified how a key infection-fighting function is involved in triggering hyperactive behaviors in mice. The finding, appearing this month in the journal Brain, Behavior, and Immunity, adds insight to an on-off switch for genes called STAT1.
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Oct 15, 2024 | 
medicalxpress.com | Sarah Avery
This article has been reviewed according to Science X's editorial process and policies . Editors have highlighted the following attributes while ensuring the content's credibility:Black men with advanced prostate cancer have a greater chance of survival after immunotherapy treatment, at least in part, because of ancestral gene variants in immune responses.
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May 9, 2024 | 
medicalxpress.com | Sarah Avery
A team led by the Duke Human Vaccine Institute (DHVI) has developed a vaccine approach that works like a GPS, guiding the immune system through the specific steps to make broadly neutralizing antibodies against HIV. Publishing in the journal Cell Host & Microbe, the study describes an approach that provides step-by-step directions for the immune system to generate the elusive, yet necessary antibodies for a successful HIV vaccine. "HIV is the fastest-evolving virus known.
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Feb 29, 2024 | 
medicalxpress.com | Sarah Avery
In a finding that could help reduce the racial disparity in kidney disease, Duke Health researchers have detailed how two common gene variants among African Americans can cause kidney failure. The finding, reported in the Journal of Clinical Investigation, could point to new treatment approaches and advance investigational therapies that block the gene.
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Feb 26, 2024 | 
medicalxpress.com | Sarah Avery
Regardless of socioeconomic factors and tumor variables, Black women with triple negative breast cancer have a significantly poorer response to chemotherapy than white women, researchers at Duke Cancer Institute report. The finding, published online Feb. 23 in the Journal of Clinical Oncology, suggests that this type of aggressive cancer may not be the same tumor in all patients, contributing to differences in treatment outcomes for racial and ethnic groups.
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Jan 15, 2024 | 
medicalxpress.com | Sarah Avery
While the risks of drug use, smoking and drinking during pregnancy are widely accepted, a new survey of parents has identified clear associations between certain types of childhood cancers and gestational substance use, notably cannabis. The study—led by Duke Health and appearing in the journal Cancer Epidemiology, Biomarkers, and Prevention—adds specificity to the potential harms of drug and alcohol use during pregnancy.
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Jan 5, 2024 | 
medicalxpress.com | Sarah Avery
The path to a successful HIV vaccine depends on a critical first step—activating specific immune cells that induce broadly neutralizing antibodies. Reporting Jan. 4 in the journal Cell, a research team led by the Duke Human Vaccine Institute has achieved that requisite initial step in a study using monkeys. The next phase of the work will now move to testing in humans.
