Sarah J Holdsworth-Carson

1 month ago | biorxiv.org | Claire Miller |Domenic P.J. Germano |Alicia M. Chenoweth |Sarah J Holdsworth-Carson

AbstractThe immune system is hypothesised to contribute to the onset of endometriosis lesions. However, the precise mechanisms underlying its role are not yet known. We introduce a novel compartmental model that describes the interactions between innate immune cells, specifically macrophages and natural killer cells, and endometrial cells, occurring within the peritoneal fluid during the early stages of superficial peritoneal) endometriosis lesion onset.