Sarah Merrill

Featured in: Favicon

news.com.au Favicon

jamanetwork.com Favicon

couriermail.com.au Favicon

seventeen.com Favicon

pedestrian.tv Favicon

dvidshub.net Favicon

fatherly.com Favicon

brobible.com + 9 more

Articles

Considerations for Cell Type Heterogeneity in Pediatric Salivary DNA Methylation Analyses: Comparison of Reference Panels & Stratification by Estimated Cell Type Proportion | bioRxiv

Nov 11, 2024 | biorxiv.org | Mandy Meijer |Sarah Merrill |David Lin |Meingold Hiu-Ming Chan

AbstractSaliva is a widely used sample in epigenetic research with children due to its non-invasive nature. Since DNA methylation (DNAm) profile is cell type (CT) specific, salivary DNAm associations with exposures may be influenced by CT compositions, which is highly variable in saliva as it contains immune and buccal epithelial cells (BEC). Reference-based CT deconvolution and statistically adjusting estimated CT in DNAm analyses have become an increasingly common practice.

Contact details

Emails

[email protected]

Socials & Sites

Try JournoFinder For Free

Search and contact over 1M+ journalist profiles, browse 100M+ articles, and unlock powerful PR tools.

Start Your 7-Day Free Trial →